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Lenome 10mg - Lenalidomide Capsules

Lenome 10mg is an oral anti-cancer medication used to treat various blood cancers such as multiple myeloma and myelodysplastic syndromes. It works by modifying the immune system, suppressing cancer cell growth, and preventing the development of blood vessels that feed tumors.

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General Information:
Generic Name: Lenalidomide
Brand Name: Lenome 10mg
Packing: Usually available in strips or bottles containing 10 or 30 capsules
Strength: 10 mg
Manufacturer: Intas Pharmaceuticals Ltd.
Form: Capsule (Oral)
Category: Immunomodulatory Agent / Anti-cancer Drug
Product Introduction:
Lenome 10mg, manufactured by Intas Pharmaceuticals Ltd., is a potent immunomodulatory agent primarily prescribed for hematological malignancies. Its effectiveness in treating multiple myeloma and other cancers has made it an essential drug in modern oncology regimens.

Uses:
Lenome 10mg is used in the treatment of:
  1. Multiple Myeloma – in combination with dexamethasone and other drugs.
  2. Myelodysplastic Syndromes (MDS) – especially with deletion 5q abnormality.
  3. Mantle Cell Lymphoma (MCL) – in patients who have failed prior treatment.
  4. Chronic Lymphocytic Leukemia (CLL) – as a second-line therapy.
  5. Follicular Lymphoma – in clinical settings or relapsed conditions.
  6. Cutaneous T-cell Lymphoma (CTCL) – in refractory or advanced cases.

Storage Instructions:
  1. Store at a temperature below 25°C.
  2. Protect from moisture, light, and heat.
  3. Keep the capsules in their original blister pack.
  4. Keep out of reach of children and pets.

How It Works (Mechanism of Action):
Lenalidomide, the active compound in Lenome 10mg, enhances immune system activity by stimulating T-cells and natural killer (NK) cells. It inhibits angiogenesis (formation of new blood vessels in tumors), induces apoptosis (cell death) in malignant cells, and alters the tumor microenvironment to suppress cancer growth.

Side Effects:
Common side effects:
  1. Tiredness or fatigue
  2. Nausea or constipation
  3. Skin rash
  4. Low blood cell counts (anemia, neutropenia, thrombocytopenia)
  5. Muscle cramps
  6. Dizziness
Serious side effects:
  1. Blood clots (deep vein thrombosis, pulmonary embolism)
  2. Liver toxicity
  3. Severe skin reactions (e.g., Stevens-Johnson Syndrome)
  4. Tumor lysis syndrome
  5. Infections due to low white blood cells
  6. Increased risk of secondary cancers

Dosage (Typical Recommended Dose):
  1. The standard dose is 10 mg once daily for 21 days of a 28-day treatment cycle.
  2. Dosing may be modified depending on the disease, kidney function, and patient's tolerance.
  3. Always follow the oncologist's prescription and recommendations.

Method of Administration:
  1. Take Lenome 10mg orally with a full glass of water.
  2. Swallow the capsule whole; do not crush, chew, or open it.
  3. It can be taken with or without food.
  4. Take it at the same time every day for best results.

Precautions:
  1. Strictly avoid use during pregnancy due to risk of severe birth defects.
  2. Both men and women should use reliable contraception during and after treatment.
  3. Do not donate blood or sperm while on this medication.
  4. Regular monitoring of blood counts and organ function is required.
  5. Inform your doctor if you have a history of blood clots, liver, kidney, or heart problems.

Drug Interactions: 
Inform your doctor if you are taking any of the following:
  1. Dexamethasone (increases clotting risk)
  2. Anticoagulants (e.g., warfarin, enoxaparin)
  3. Erythropoiesis-stimulating agents
  4. Other chemotherapy or immunomodulatory drugs
  5. Live vaccines – should be avoided during treatment

Allergies:
  1. Avoid Lenome 10mg if you have a known allergy to Lenalidomide or similar compounds.
  2. Signs of allergic reaction include: rash, itching, swelling, dizziness, and trouble breathing.
  3. Discontinue and seek medical help immediately if allergic reactions occur.

Overdose Information:
  1. In case of suspected overdose, seek emergency medical attention immediately.
  2. Symptoms may include severe fatigue, dizziness, fainting, or excessive bleeding.
  3. No specific antidote exists; treatment is supportive and based on symptoms.

Missed Dose Instructions:
  1. If a dose is missed and it’s less than 12 hours late, take it as soon as remembered.
  2. If more than 12 hours have passed, skip the missed dose.
  3. Do not double the dose to make up for a missed one.

Additional Notes:
  1. This medication may be distributed under a controlled program (e.g., REMS).
  2. Women of childbearing age must undergo pregnancy testing before and during treatment.
  3. Avoid donating blood or organs while on this drug.
  4. Caregivers should wear gloves when handling capsules.
  5. Patients should carry a treatment card or ID noting their use of Lenalidomide.
  6. Notify your healthcare provider about any unusual symptoms or bleeding.

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