Product Intro:
Botox 100iu is a widely recognized and clinically approved injectable neuromodulator. Derived from Clostridium botulinum, it blocks nerve signals to muscles, helping reduce abnormal contractions and the appearance of facial wrinkles. It is also used in managing chronic medical conditions such as muscle spasticity, migraines, and hyperhidrosis.
Uses:
Botox 100iu is indicated for multiple therapeutic and aesthetic uses:
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Treatment of cervical dystonia (neck muscle spasms)
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Management of chronic migraines
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Severe underarm sweating (axillary hyperhidrosis)
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Blepharospasm (uncontrollable blinking)
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Strabismus (crossed eyes)
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Reduction of glabellar lines (frown lines) and crow's feet in aesthetic procedures
Storage Instructions:
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Store refrigerated between 2°C to 8°C before reconstitution
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After reconstitution, use within 24 hours and store in a refrigerator
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Do not freeze reconstituted solution
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Keep vial protected from light and out of reach of children
How it Works (Mechanism of Action):
Botulinum toxin type A inhibits the release of acetylcholine at neuromuscular junctions. This blocks the transmission of nerve impulses to the muscle, leading to temporary muscle relaxation or paralysis. The effect helps reduce spasticity, pain, and muscle contractions in therapeutic use and smooths wrinkles in cosmetic procedures.
Side Effects:
Common Side Effects:
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Injection site pain or swelling
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Mild headache
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Dry eyes or tearing
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Temporary muscle weakness near the injection site
Severe Side Effects:
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Difficulty breathing or swallowing (rare but serious)
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Drooping eyelids (ptosis)
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Severe allergic reactions (anaphylaxis)
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Loss of bladder control (in therapeutic use for overactive bladder)
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Flu-like symptoms or generalized muscle weakness
Dosage (Typical Recommended Dose):
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Varies depending on indication, muscle mass, and patient condition
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For cosmetic use (glabellar lines): 20 IU injected into 5 sites
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For chronic migraine: Up to 155 IU in divided doses across 31 sites
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For cervical dystonia: 200-300 IU total per session
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Always administered by a qualified healthcare provider
Method of Administration:
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Intramuscular injection into targeted muscles
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Should be reconstituted with sterile saline before use
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Administered using a fine-gauge needle
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Only to be used by trained medical professionals
Precautions:
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Not recommended in patients with a known hypersensitivity to botulinum toxin
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Use caution in patients with neuromuscular disorders (e.g., myasthenia gravis)
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Avoid during active infection or inflammation at the proposed injection site
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Inform your doctor if pregnant or breastfeeding
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Avoid alcohol and blood thinners before the procedure (to reduce bruising)
Drug Interactions:
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Aminoglycoside antibiotics (e.g., gentamicin) may enhance botulinum effects
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Muscle relaxants may increase the risk of excessive muscle weakness
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Other botulinum toxin products should be avoided concurrently
Allergies:
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Contraindicated in patients with a history of allergy to botulinum toxin or formulation ingredients (e.g., albumin)
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Watch for symptoms like rash, itching, swelling of the face or throat, or difficulty breathing
Overdose Information:
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Overdose can lead to botulism-like symptoms such as severe muscle weakness, respiratory depression, or paralysis
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Immediate hospitalization and supportive care are required in suspected overdose cases
Missed Dose Instructions:
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Since Botox is given in a clinical setting, the risk of missed doses is minimal
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Follow-up sessions should be scheduled as recommended by the healthcare provider
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Effects typically last 3 to 4 months
Additional Notes:
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Results may start appearing within 24–72 hours after injection, with peak effects at 1–2 weeks
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Long-term use should be spaced adequately to prevent antibody formation
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Botox should not be interchanged with other botulinum toxin brands due to differences in potency
