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Encicarb 500mg - Ferric Carboxymaltose Injection

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Encicarb 500mg - Ferric Carboxymaltose Injection

Encicarb 500mg is an iron replacement injection used to treat iron deficiency anemia, especially when oral iron supplements are ineffective or not well-tolerated. It delivers iron directly into the bloodstream for rapid replenishment of iron stores.

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Description Product Details
General Information:
Generic Name: Ferric Carboxymaltose
Brand Name: Encicarb
Packing: Single-use vial
Strength: 500mg/10ml
Manufacturer: Emcure Pharmaceuticals Ltd.
Form: Injection (Intravenous)
Category: Iron supplement, Antianemic
Product Intro:
Encicarb 500mg is a high-dose intravenous iron therapy developed by Emcure Pharmaceuticals. It is specially formulated for patients with iron deficiency anemia due to chronic conditions such as kidney disease, inflammatory bowel disease, or heavy menstrual bleeding, where oral iron fails or cannot be tolerated.
Uses:
Encicarb 500mg is used for the treatment of:
  1. Iron deficiency anemia in chronic kidney disease (CKD)
  2. Iron deficiency anemia in inflammatory bowel disease (IBD)
  3. Iron deficiency due to heavy menstrual bleeding
  4. Iron deficiency in postpartum women
  5. Iron deficiency in patients intolerant to oral iron
  6. Rapid iron replenishment in surgical or oncology patients
Storage Instructions:
  1. Store between 15°C to 25°C
  2. Protect from light and moisture
  3. Do not freeze
  4. Keep out of reach of children
How it Works (Mechanism of Action):
Ferric carboxymaltose is a stable iron complex. Once administered intravenously, it releases iron slowly into the bloodstream, where it is taken up by the body's natural iron transport proteins. This allows quick restoration of iron levels and supports the production of healthy red blood cells.
Side Effects:
Common Side Effects:
  1. Headache
  2. Dizziness
  3. Injection site reactions
  4. Nausea
  5. Flushing
  6. Hypophosphatemia (low phosphate levels)
Serious Side Effects:
  1. Hypersensitivity reactions
  2. Hypotension
  3. Anaphylaxis (rare)
  4. Elevated liver enzymes
Dosage (Typical Recommended Dose):
  1. 500mg to 1000mg (single dose based on body weight and hemoglobin levels)
  2. May be repeated after 1 week if needed, under doctor’s supervision
Method of Administration:
  1. Administered intravenously (IV)
  2. Can be given as an IV bolus injection or infusion over 15 minutes
  3. Must be administered under the supervision of a healthcare professional
Precautions:
  1. Use with caution in patients with liver dysfunction or history of iron overload
  2. Monitor phosphate levels in patients requiring repeat doses
  3. Avoid use in patients with active infection
  4. Not recommended during the first trimester of pregnancy
  5. Always perform a test dose in high-risk individuals
Drug Interactions:
  1. May interact with oral iron supplements (avoid concurrent use)
  2. Monitor in patients on erythropoiesis-stimulating agents (ESAs)
  3. Use cautiously with antihypertensive drugs due to risk of hypotension
Allergies:
  1. Contraindicated in patients with known hypersensitivity to ferric carboxymaltose or any of its excipients
  2. Watch for signs of allergic reactions like rash, itching, difficulty breathing, or swelling
Overdose Information:
  1. Iron overdose can cause iron toxicity leading to metabolic acidosis, liver damage, or death
  2. In case of overdose, provide supportive treatment and monitor iron parameters
Missed Dose Instructions:
  1. If a dose is missed, contact the healthcare provider for rescheduling
  2. Do not attempt to self-administer the missed dose
Additional Notes:
  1. Oral iron supplements should be stopped at least 5 days before starting Encicarb
  2. Suitable for outpatient or hospital administration
  3. Iron levels, hemoglobin, and ferritin should be monitored periodically

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